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Causes of Rickets



Rickets is a nutritional deficiency disease caused due to deficiency of vitamin D. This disease occurs in children. In rickets, before the epiphyses have fused, there occurs failure of growing bone to mineralize due to deficiency of vitamin D in growing child.


Causes-  
                                                                                                                                             

1.      Due to malabsorption syndrome or state.

2.      Chronic renal failure.

3.      Underlying malignant disease.

4.      Side effects of some allopathic medicines.

5.      Resistant to ordinary therapeutic doses of vitamin D.

6.      Coeliac disease.

7.      Inadequate intake of calcium in diet.

8.      Inadequate intake of vitamin D in diet.

9.      Intestinal resection.

10.  Genetic defect in production of enzyme renal 25(OH)D3-1-α-hydroxylase.

11.  Occurs more in dark skinned persons as melanin acts as a neutral filter and absorbs solar radiation. Therefore, dark skinned persons require more sunlight exposure to synthesize vitamin D.

Do you know about- Tests to Identify Malabsorption Syndrome
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