Congenital Adrenal Hyperplasia

The most common enzyme defect in congenital hyperplasia is 21-hydroxylase deficiency. This enzyme defect is inherited as autosomal recessive trait.

Symptoms-

1. Glucocorticoid deficiency.

2. Mineralocorticoid deficiency.

3. Androgen excess.

4. Cortisol insufficiency.

5. ACTH and androgen excess.

6. Amenorrhea.

7. Hypertension.

Investigations-

Plasma 170H progesterone.

Management-

1. Replace deficient corticosteroids.

2. Suppress ACTH.

Do you know about- Renal Abscess

Chronic Pyelonephritis

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