Aplastic anaemia is a disease in which there occurs pancytopenia due to the presence of acellular or markedly hypocellular bone marrow but there is no leukaemic or abnormal cells in marrow or blood.
Types-
It is classified into two types-
2. Acquired aplastic anaemia.
Causes-
There are so many causes of aplastic anemia, which are as follow-
2. Harmful effects of chemicals.
3. Viral infections.
4. Pancreatitis.
5. Radiation.
Symptoms-
2. Dyspnoea on exertion.
3. Pallor.
4. Granulocytopenia.
5. Sore throat, oral and pharyngeal ulcers, fever.
6. Chronic skin infections.
7. Recurrent respiratory infections.
8. Thrombocytopenia.
Investigations-
2. Corrected reticulocyte count test.
3. TLC and DLC tests.
4. Peripheral blood smear test.
5. Bone marrow test.
6. Serum transferrin test.
7. Serum iron test.
8. Platelet count test.
Treatment-
2. Prevention and treatment of infections and bleeding.
3. Red cell transfusion for severe anaemia only where indicated under doctor’s supervision.
4. Bone marrow transplantation in patients under the age of fifty years.
5. Medicinal treatment.
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